Monoclonal gammopathies: Electronic subspecialty consultation

Eur J Haematol. 2018 Apr;100(4):351-355. doi: 10.1111/ejh.13019. Epub 2018 Jan 31.

Abstract

Importance: Electronic consultation (e-consult) is an important component of care for patients in the Veterans Health Administration who require subspecialty consultation but not urgent face-to-face evaluation. Monoclonal gammopathy of undetermined significance (MGUS) is a common reason for e-consult. While often benign, MGUS requires careful evaluation and persistent surveillance over time.

Objective: To identify areas to improve MGUS care delivery by e-consult.

Methods: We performed a retrospective review of our e-consult database and identified a cohort of 152 MGUS patients triaged for e-consult over a 5-year period (2010-2014).

Results: The median time to completion of an e-consult was 2 days. Ninety-six percent of MGUS e-consults had a hemoglobin >10 g/dL, and 90% had a creatinine <2 mg/dL. While the majority of e-consults were low risk, paraprotein surveillance varied over time and tracked with consult utilization. With a median follow-up of 44 months, there were 6 documented progression events, representing a mean rate of progression of 1% per year.

Conclusions: E-consult is a helpful mechanism for the evaluation of MGUS, reducing the need for outpatient appointments. However, timely risk stratification and persistent surveillance over time are critical for e-consult to work well.

Keywords: electronic consultation; monoclonal gammopathy; monoclonal gammopathy of undetermined significance; multiple myeloma.

Publication types

  • Review

MeSH terms

  • Aged
  • Biomarkers
  • Biopsy
  • Delivery of Health Care
  • Disease Management
  • Electronic Health Records
  • Female
  • Follow-Up Studies
  • Hematologic Tests
  • Humans
  • Male
  • Middle Aged
  • Monoclonal Gammopathy of Undetermined Significance / diagnosis
  • Monoclonal Gammopathy of Undetermined Significance / therapy
  • Paraproteinemias / diagnosis*
  • Paraproteinemias / therapy*
  • Quality Improvement
  • Remote Consultation* / methods
  • Retrospective Studies
  • Risk Assessment

Substances

  • Biomarkers