Heart Failure: Epidemiology, Pathophysiology, and Management of Heart Failure in Diabetes Mellitus

Anders Jorsal; Henrik Wiggers; John J V McMurray

doi:10.1016/j.ecl.2017.10.007

Heart Failure: Epidemiology, Pathophysiology, and Management of Heart Failure in Diabetes Mellitus

Endocrinol Metab Clin North Am. 2018 Mar;47(1):117-135. doi: 10.1016/j.ecl.2017.10.007. Epub 2017 Dec 8.

Authors

Anders Jorsal¹, Henrik Wiggers¹, John J V McMurray²

Affiliations

¹ Department of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, Denmark; Department of Clinical Medicine, Aarhus University, Incuba Skejby, Building 2, Palle Juul-Jensens Boulevard 82, 8200 Aarhus N, Denmark.
² BHF Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, 126 University Place, Glasgow G12 8TA, UK; Queen Elizabeth University Hospital, 1345 Govan Road, Glasgow G51 4TF, UK. Electronic address: JOHN.MCMURRAY@GLASGOW.AC.UK.

PMID: 29407047
DOI: 10.1016/j.ecl.2017.10.007

Abstract

This article briefly discusses the epidemiology of heart failure and diabetes and summarizes the key findings from the recent cardiovascular outcome trials in patients with type 2 diabetes, with a focus on heart failure as an endpoint.

Keywords: Cardiac function; Cardiovascular events; Glucose lowering therapy; Glycemia; Heart failure; Type 2 diabetes mellitus.

Publication types

Review

MeSH terms

Comorbidity*
Diabetes Mellitus, Type 2* / drug therapy
Diabetes Mellitus, Type 2* / epidemiology
Heart Failure* / drug therapy
Heart Failure* / epidemiology
Heart Failure* / physiopathology
Humans
Hypoglycemic Agents / adverse effects
Hypoglycemic Agents / pharmacology*

Substances

Hypoglycemic Agents