Heptyl vicianoside and methyl caramboside from sour star fruit

Nat Prod Res. 2019 Apr;33(8):1233-1236. doi: 10.1080/14786419.2018.1466123. Epub 2018 Apr 23.

Abstract

Two new alkyl glycosides, heptyl vicianoside (1) and methyl 2-O-β-d-fucopyranosyl-α-l-arabinofuranoside (methyl caramboside, 4), were isolated from the sour fruit of Averrhoa carambola L. (Oxalidaceae), along with octyl vicianoside (2), cis-3-hexenyl rutinoside (3), and methyl α-d-fructofuranoside (5). Their structures were determined by spectroscopic and chemical methods. Compounds 2, 3, and 5 were obtained from the genus Averrhoa for the first time. All the compounds were evaluated for in vitro α-glucosidase, pancreatic lipase, and acetylcholinesterase inhibitory activities, but none of them were potent.

Keywords: heptyl vicianoside; methyl caramboside; star fruit.

MeSH terms

  • Averrhoa / chemistry*
  • Cholinesterase Inhibitors
  • Fruit / chemistry*
  • Glycoside Hydrolase Inhibitors
  • Glycosides / analysis
  • Glycosides / isolation & purification*
  • Glycosides / pharmacology
  • Lipase / antagonists & inhibitors
  • Molecular Structure
  • Oxalidaceae / chemistry
  • Spectrum Analysis

Substances

  • Cholinesterase Inhibitors
  • Glycoside Hydrolase Inhibitors
  • Glycosides
  • Lipase