Complete Genome Sequence of Escherichia coli AS19, an Antibiotic-Sensitive Variant of E. coli Strain B REL606

Mariana Avalos; Marten Boetzer; Walter Pirovano; Nelson E Arenas; Stephen Douthwaite; Gilles P van Wezel

doi:10.1128/genomeA.00385-18

Complete Genome Sequence of Escherichia coli AS19, an Antibiotic-Sensitive Variant of E. coli Strain B REL606

Genome Announc. 2018 May 3;6(18):e00385-18. doi: 10.1128/genomeA.00385-18.

Authors

Mariana Avalos¹, Marten Boetzer², Walter Pirovano², Nelson E Arenas³, Stephen Douthwaite³, Gilles P van Wezel⁴

Affiliations

¹ Institute of Biology, Leiden University, Leiden, The Netherlands.
² Bioinformatics Department, BaseClear BV, Leiden, The Netherlands.
³ Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.
⁴ Institute of Biology, Leiden University, Leiden, The Netherlands g.wezel@biology.leidenuniv.nl.

Abstract

The chemically mutagenized Escherichia coli strain AS19 was isolated on the basis of its enhanced sensitivity to different antibiotics, in particular to actinomycin. The strain was later modified to study rRNA modifications that confer antibiotic resistance. Here, we present the genome sequence of the variant E. coli AS19-RrmA.