Pulmonary Neuroendocrine Cells: Sensors and Sentinels of the Lung

Yoshihiko Kobayashi; Purushothama Rao Tata

doi:10.1016/j.devcel.2018.05.009

Pulmonary Neuroendocrine Cells: Sensors and Sentinels of the Lung

Dev Cell. 2018 May 21;45(4):425-426. doi: 10.1016/j.devcel.2018.05.009.

Authors

Yoshihiko Kobayashi¹, Purushothama Rao Tata²

Affiliations

¹ Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA.
² Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA; Duke Cancer Institute, Duke University Medical Center, Durham, NC 27710, USA; Regeneration Next, Duke University, Durham, NC 27710, USA. Electronic address: purushothamarao.tata@duke.edu.

PMID: 29787707
DOI: 10.1016/j.devcel.2018.05.009

Abstract

Organisms have developed cellular "antennas" to sense, interpret, and integrate environmental stimuli. In a recent issue of Science, Sui et al. (2018) demonstrate that discrete clusters of pulmonary neuroendocrine cells in the lung can sense airborne allergens and relay signals to stimulate immune cells and induce tissue/organ-wide responses.

Publication types

Comment

MeSH terms

Lung*
Neuroendocrine Cells*