Vertical Transmission of Mycoplasma pneumoniae Infection

Benedikt M Huber; Patrick M Meyer Sauteur; Wendy W J Unger; Paul Hasters; Marcel R Eugster; Simone Brandt; Guido V Bloemberg; Giancarlo Natalucci; Christoph Berger

doi:10.1159/000490610

Vertical Transmission of Mycoplasma pneumoniae Infection

Neonatology. 2018;114(4):332-336. doi: 10.1159/000490610. Epub 2018 Aug 8.

Authors

Benedikt M Huber¹, Patrick M Meyer Sauteur², Wendy W J Unger³, Paul Hasters¹, Marcel R Eugster⁴, Simone Brandt⁵, Guido V Bloemberg⁶, Giancarlo Natalucci¹, Christoph Berger^{7

8}

Affiliations

¹ Department of Neonatology, University Hospital Zurich, Zurich, Switzerland.
² Division of Infectious Diseases and Hospital Epidemiology, and Children's Research Center (CRC), University Children's Hospital Zurich, Zurich, Switzerland.
³ Laboratory of Pediatrics, Division of Pediatric Infectious Diseases and Immunology, Erasmus MC University Medical Center - Sophia Children's Hospital, Rotterdam, the Netherlands.
⁴ Unilabs Duebendorf, Molecular Diagnostics, Duebendorf, Switzerland.
⁵ Institute of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland.
⁶ Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland.
⁷ Division of Infectious Diseases and Hospital Epidemiology, and Children's Research Center (CRC), University Children's Hospital Zurich, Zurich, Switzerlandchristoph.berger@kispi.uzh.ch.
⁸ Institute of Medical Microbiology, University of Zurich, Zurich, Switzerlandchristoph.berger@kispi.uzh.ch.

PMID: 30089291
DOI: 10.1159/000490610

Abstract

Mycoplasma pneumoniae is a significant cause of pneumonia in school-aged children and young adults. We report a case of neonatal M. pneumoniae pneumonia in a preterm child manifesting in the first hours of life. Vertical transmission was demonstrated by the detection of M. pneumoniae in inflamed placental tissue indicating chorioamnionitis.

Keywords: Congenital infection; Mycoplasma pneumoniae; Neonatal pneumonia; Vertical transmission.

Publication types

Case Reports
Review

MeSH terms

Chorioamnionitis / microbiology
DNA, Bacterial / isolation & purification
Female
Humans
Infant, Newborn
Infectious Disease Transmission, Vertical*
Male
Mycoplasma pneumoniae / isolation & purification*
Placenta / microbiology
Pneumonia, Mycoplasma / congenital*
Pneumonia, Mycoplasma / diagnosis
Pneumonia, Mycoplasma / therapy
Pneumonia, Mycoplasma / transmission*
Pregnancy
Radiography, Thoracic

Substances

DNA, Bacterial