Low-level ozone has both respiratory and systemic effects in African American adolescents with asthma despite asthma controller therapy

J Allergy Clin Immunol. 2018 Dec;142(6):1974-1977.e3. doi: 10.1016/j.jaci.2018.08.003. Epub 2018 Aug 10.

Abstract

In a cohort of African American adolescents with persistent asthma on guidelines-based daily controller therapies, short–term elevation of low ozone levels below the National Ambient Air Quality Standard of 70 ppb were associated with lung function decrements and elevated lipid levels.

Publication types

  • Letter
  • Observational Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adolescent
  • Air Pollutants / toxicity*
  • Anti-Asthmatic Agents / therapeutic use
  • Asthma / blood*
  • Asthma / drug therapy
  • Asthma / physiopathology*
  • Child
  • Cholesterol / blood*
  • Female
  • Forced Expiratory Volume
  • Humans
  • Male
  • Ozone / toxicity*
  • Vital Capacity

Substances

  • Air Pollutants
  • Anti-Asthmatic Agents
  • Ozone
  • Cholesterol