Melanopsin Shows Its (Contrast-)Sensitive Side

Joseph Pottackal; Jonathan B Demb

doi:10.1016/j.neuron.2018.08.007

Melanopsin Shows Its (Contrast-)Sensitive Side

Neuron. 2018 Aug 22;99(4):630-632. doi: 10.1016/j.neuron.2018.08.007.

Authors

Joseph Pottackal¹, Jonathan B Demb²

Affiliations

¹ Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06511, USA.
² Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06511, USA; Department of Ophthalmology and Visual Science, Yale University, New Haven, CT 06511, USA; Department of Cellular and Molecular Physiology, Yale University, New Haven, CT 06511, USA. Electronic address: jonathan.demb@yale.edu.

PMID: 30138585
DOI: 10.1016/j.neuron.2018.08.007

Abstract

Melanopsin is a photopigment expressed by certain types of retinal ganglion cells that mediate non-image-forming visual functions, such as circadian photoentrainment. In this issue of Neuron, Sonoda et al. (2018) reveal how melanopsin also regulates the sensitivity of conventional image-forming vision.

Publication types

Comment

MeSH terms

Light Signal Transduction*
Retinal Ganglion Cells
Rod Opsins*
Vision, Ocular

Substances

Rod Opsins
melanopsin

Grants and funding

R01 EY014454/EY/NEI NIH HHS/United States