The manuscript 'Efficient decellularization of whole porcine kidneys improves reseeded cell behavior' (Poornejad et al 2016 Biomedical Materials 11: 025003) describes our efforts to improve the process for recellularization of porcine kidneys. We obtained what we believed to be an immortalized cell line of human renal cortical tubular epithelium (RCTE) cells from the Feinberg School of Medicine, Northwestern University to conduct our reseeding experiments. The RCTE cells that were provided to us were later discovered to actually be Madin-Darby Canine Kidney (MDCK) epithelial cells. A published erratum pertaining to this issue has been published (Caralt et al 2017 American Journal of Transplantation 17: 1429). Despite being of canine origin, MDCK cells are a distal tubule epithelial cell line that behave similarly to human RCTE cells. The conclusions regarding reseeding as reported in our paper are still sound.
Keywords: cell-ECM interaction; decellularization; kidney; organ regeneration.
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