Abstract
Both co-trimoxazole and pentamidine are used for the treatment of pneumocystis pneumonia (PCP) and are known to cause hypoglycemia as an adverse drug reaction. Here, we describe a rare case of a late-diagnosed female patient with acquired immunodeficiency syndrome (AIDS) who developed the first hypoglycemic attack as an adverse effect of co-trimoxazole, followed by a second hypoglycemic attack as an adverse effect of pentamidine. Physicians caring for patients with AIDS and PCP should be aware of possible hypoglycemia in patients with many risk factors.
Keywords:
Hypoglycemia; Pneumocystis pneumonia; co-trimoxazole; pentamidine.
MeSH terms
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Acquired Immunodeficiency Syndrome / drug therapy
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Aged
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Anti-Infective Agents / therapeutic use*
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Atovaquone / therapeutic use*
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Drug-Related Side Effects and Adverse Reactions
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Female
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Humans
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Hypoglycemia / chemically induced*
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Pentamidine / adverse effects*
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Pentamidine / therapeutic use
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Pneumonia, Pneumocystis / complications
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Pneumonia, Pneumocystis / drug therapy*
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Treatment Outcome
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Trimethoprim, Sulfamethoxazole Drug Combination / adverse effects*
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Trimethoprim, Sulfamethoxazole Drug Combination / therapeutic use
Substances
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Anti-Infective Agents
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Pentamidine
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Trimethoprim, Sulfamethoxazole Drug Combination
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Atovaquone