Takotsubo syndrome and dialysis: an uncommon association?

J Int Med Res. 2018 Nov;46(11):4399-4406. doi: 10.1177/0300060518794249. Epub 2018 Sep 4.

Abstract

This review was performed to investigate the association between treatment with dialysis and Takotsubo syndrome in patients with end-stage renal disease. We systematically explored the PubMed database using the search terms "Takotsubo cardiomyopathy" and/or "stress-induced cardiomyopathy" and/or "Takotsubo syndrome" in combination with "dialysis" and "uremia." Of 3630 articles found, 8 articles reporting 10 cases were selected for analysis. Most patients were women, and their age ranged from 51 to 84 years. Diabetes mellitus and hypertension were diagnosed in 40% of patients, and glomerular disease was diagnosed in 30%. One only patient was treated with peritoneal dialysis; all others were treated with hemodialysis. The outcome was unfavorable in only one patient. An association between Takotsubo syndrome and dialysis is uncommon, but not negligible, and comorbidities play a major role in determining the clinical outcome.

Keywords: Takotsubo syndrome; cardiomyopathy; dialysis; end-stage renal disease; outcome; review; sex.

Publication types

  • Systematic Review

MeSH terms

  • Aged
  • Aged, 80 and over
  • Female
  • Humans
  • Male
  • Middle Aged
  • Renal Dialysis / adverse effects*
  • Takotsubo Cardiomyopathy / etiology*