Clinical Implication of Multi-Parameter Flow Cytometry in Myelodysplastic Syndromes

Abstract

Myelodysplastic syndromes (MDS) are a challenging group of diseases for clinicians and researchers, as both disease course and pathobiology are highly heterogeneous. In (suspected) MDS patients, multi-parameter flow cytometry can aid in establishing diagnosis, risk stratification and choice of therapy. This review addresses the developments and future directions of multi-parameter flow cytometry scores in MDS. Additionally, we propose an integrated diagnostic algorithm for suspected MDS.

Keywords: Diagnosis; Flow cytometry; Myelodysplastic syndromes.