Brigatinib versus crizotinib for ALK-positive NSCLC

Lancet Oncol. 2018 Nov;19(11):e585. doi: 10.1016/S1470-2045(18)30741-1. Epub 2018 Oct 4.
No abstract available

Publication types

  • News

MeSH terms

  • Anaplastic Lymphoma Kinase / antagonists & inhibitors*
  • Anaplastic Lymphoma Kinase / genetics
  • Antineoplastic Agents / adverse effects
  • Antineoplastic Agents / therapeutic use*
  • Carcinoma, Non-Small-Cell Lung / drug therapy*
  • Carcinoma, Non-Small-Cell Lung / enzymology
  • Carcinoma, Non-Small-Cell Lung / genetics
  • Carcinoma, Non-Small-Cell Lung / mortality
  • Clinical Trials, Phase III as Topic
  • Crizotinib / adverse effects
  • Crizotinib / therapeutic use*
  • Humans
  • Lung Neoplasms / drug therapy*
  • Lung Neoplasms / enzymology
  • Lung Neoplasms / genetics
  • Lung Neoplasms / mortality
  • Multicenter Studies as Topic
  • Organophosphorus Compounds / adverse effects
  • Organophosphorus Compounds / therapeutic use*
  • Progression-Free Survival
  • Protein Kinase Inhibitors / adverse effects
  • Protein Kinase Inhibitors / therapeutic use*
  • Pyrimidines / adverse effects
  • Pyrimidines / therapeutic use*
  • Randomized Controlled Trials as Topic
  • Time Factors

Substances

  • Antineoplastic Agents
  • Organophosphorus Compounds
  • Protein Kinase Inhibitors
  • Pyrimidines
  • Crizotinib
  • ALK protein, human
  • Anaplastic Lymphoma Kinase
  • brigatinib