Diagnostic radiation-induced regression of a metastatic primary intracranial germinoma: a case report

Br J Neurosurg. 2022 Apr;36(2):258-261. doi: 10.1080/02688697.2018.1519110. Epub 2018 Nov 4.

Abstract

Pineal region germinomas are sensitive to radiotherapy. Standard neurosurgical management involves obtaining a tissue biopsy and to relieve the often accompanying obstructive hydrocephalus. We present a patient with a suspected hyper-radiosensitive metastatic primary intracranial germinoma where computed tomography scanning resulted in tumor regression before radiotherapy could be administered.

Keywords: computed tomography; germinoma; radiotherapy; tumor regression.

Publication types

  • Case Reports

MeSH terms

  • Biopsy / adverse effects
  • Brain Neoplasms* / diagnostic imaging
  • Brain Neoplasms* / pathology
  • Brain Neoplasms* / radiotherapy
  • Germinoma* / diagnostic imaging
  • Germinoma* / radiotherapy
  • Humans
  • Hydrocephalus* / etiology
  • Pineal Gland* / diagnostic imaging
  • Pineal Gland* / pathology