Correlation Between Blood Transfusion and Blood Glucose Levels in Adult Living Donor Liver Transplantation

Transplant Proc. 2018 Nov;50(9):2645-2647. doi: 10.1016/j.transproceed.2018.02.203. Epub 2018 Mar 19.

Abstract

Background: To evaluate the effect of dextrose contained in banked blood products on the changes of blood glucose levels in adult living donor liver transplantation patients retrospectively.

Methods: Four hundred seventy-seven patients were divided into a non-blood transfusion (BT) group (G1) and a BT group (G2). The changes in blood glucose levels during the operation were compared using a Mann-Whitney U test, and a P value less than .05 was regarded as significant.

Results: No significant changes were detected in blood glucose levels after anesthesia, during dissection phase, in the anhepatic phase, or after reperfusion between the groups. Estimated blood loss for G1 (n = 89) and G2 (n = 388) were 718 ± 514 and 5804 ± 877 mL respectively, G1 had no blood transfusion but G2 had received 4350 ± 6230 mL leukocyte-poor red blood cell transfusion, the pre- and end operation hemoglobin for G1 and G2 were 13.2 ± 2.0, 10.2 ± 1.9 and 10.1 ± 1.6, 10.2 ± 1.9 mg/dL respectively, indicating that they were not under or over transfused.

Conclusion: When banked blood products are used to replace ongoing blood loss, the dextrose contained in citrate-phosphate-dextrose-adenine seems to have no effect on the changes in the blood glucose levels of the recipients.

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Blood Banks
  • Blood Glucose / analysis*
  • Blood Transfusion / statistics & numerical data*
  • Citrates / blood
  • Female
  • Glucose
  • Hemostasis, Surgical / methods*
  • Humans
  • Liver Transplantation / methods*
  • Living Donors
  • Male
  • Middle Aged
  • Retrospective Studies
  • Statistics, Nonparametric

Substances

  • Blood Glucose
  • Citrates
  • citrate phosphate dextrose
  • Glucose