Long-Term Increase of Kcnn4 Potassium Channel Surface Expression on B Cells in Pemphigus Patients after Rituximab Treatment

J Invest Dermatol. 2018 Dec;138(12):2666-2668. doi: 10.1016/j.jid.2018.05.034. Epub 2018 Jul 2.

Authors

Frédérique Caillot¹, Céline Derambure², Nicolas Berkani¹, Gaëtan Riou³, Maud Maho-Vaillant⁴, Sébastien Calbo³, Pascal Joly⁴, Philippe Musette⁵

Affiliations

¹ Department of Dermatology, Rouen University Hospital, Rouen, France.
² Inserm U1245, IRIB, Normandie Université, Rouen, France.
³ Inserm U1234, IRIB, Normandie Université, Rouen, France.
⁴ Department of Dermatology, Rouen University Hospital, Rouen, France; Inserm U1234, IRIB, Normandie Université, Rouen, France.
⁵ Department of Dermatology, Rouen University Hospital, Rouen, France; Inserm U976 Saint Louis Hospital, Paris, France. Electronic address: philippe.musette@chu-rouen.fr.

PMID: 30472996
DOI: 10.1016/j.jid.2018.05.034

No abstract available

Publication types

Clinical Trial
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Aged
Autoimmunity
B-Lymphocytes / immunology
B-Lymphocytes / metabolism*
Cells, Cultured
Female
Follow-Up Studies
Humans
Intermediate-Conductance Calcium-Activated Potassium Channels / genetics
Intermediate-Conductance Calcium-Activated Potassium Channels / metabolism*
Male
Middle Aged
Pemphigus / drug therapy*
Pemphigus / immunology
Potassium / metabolism
Remission Induction
Rituximab / therapeutic use*
Transcriptome
Up-Regulation
Young Adult

Substances

Intermediate-Conductance Calcium-Activated Potassium Channels
KCNN4 protein, human
Rituximab
Potassium