ER stress links aging to sporadic ALS

Aging (Albany NY). 2019 Jan 5;11(1):5-6. doi: 10.18632/aging.101705.

Authors

Danilo B Medinas^#^{1

2

3}, Felipe Cabral-Miranda^#^{1

2

3

4

5}, Claudio Hetz^{1

2

3

4

6}

Affiliations

¹ Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.
² Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.
³ Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile.
⁴ Buck Institute for Research on Aging, Novato, CA 94945, USA.
⁵ Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
⁶ Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA.

^# Contributed equally.

No abstract available

Keywords: ER stress; aging; amyotrophic lateral sclerosis; protein aggregation; wild-type SOD-1.

Publication types

Editorial
Research Support, Non-U.S. Gov't

MeSH terms

Aging*
Amyotrophic Lateral Sclerosis / etiology*
Animals
Endoplasmic Reticulum Stress*
Humans
Mice
Protein Folding
Risk Factors
Superoxide Dismutase-1 / genetics
Superoxide Dismutase-1 / metabolism

Substances

Superoxide Dismutase-1