Rapid task-dependent tuning of the mouse olfactory bulb

Elife. 2019 Feb 6:8:e43558. doi: 10.7554/eLife.43558.

Abstract

Adapting neural representation to rapidly changing behavioural demands is a key challenge for the nervous system. Here, we demonstrate that the output of the primary olfactory area of the mouse, the olfactory bulb, is already a target of dynamic and reproducible modulation. The modulation depends on the stimulus tuning of a given neuron, making olfactory responses more discriminable through selective amplification in a demand-specific way.

Keywords: dynamic modulation; mouse; neuroscience; olfactory bulb; task switching.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Behavior, Animal / physiology*
  • Mice
  • Neurons / physiology*
  • Odorants / analysis
  • Olfactory Bulb / physiology*
  • Smell / physiology*