Human Spermatogonial Stem Cells Scrutinized under the Single-Cell Magnifying Glass

Kun Tan; Miles F Wilkinson

doi:10.1016/j.stem.2019.01.010

Human Spermatogonial Stem Cells Scrutinized under the Single-Cell Magnifying Glass

Cell Stem Cell. 2019 Feb 7;24(2):201-203. doi: 10.1016/j.stem.2019.01.010.

Authors

Kun Tan¹, Miles F Wilkinson²

Affiliations

¹ Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA 92093, USA.
² Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA 92093, USA; Institute of Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address: mfwilkinson@ucsd.edu.

Abstract

Spermatogonial stem cells (SSCs) are essential for adult spermatogenesis. Recently, Wang et al. (2018), Guo et al. (2018), and Hermann et al. (2018) used single-cell RNA sequencing to define and molecularly characterize human testicular cell populations, including spermatogonial subsets with characteristics of human SSCs.

Publication types

Comment

MeSH terms

Adult
Humans
Male
Sequence Analysis, RNA
Spermatogenesis*
Spermatogonia*
Stem Cells
Testis

Grants and funding

R01 GM119128/GM/NIGMS NIH HHS/United States