Aortic Bulge: A Possible Predictive Sign of Impending Aortoenteric Fistula

Can Assoc Radiol J. 2019 May;70(2):204-209. doi: 10.1016/j.carj.2018.10.012. Epub 2019 Mar 25.

Abstract

Purpose: The purpose of this study is to introduce the aortic bulge sign, a finding observed retrospectively on computed tomography prior to the acute presentation of aortoenteric fistula, and to determine its interobserver reliability.

Methods: Following research ethics board approval, all cases of aortoenteric fistula at our institution occurring from 2011-2015 were identified retrospectively. All previous computed tomography images of patients who eventually developed aortoenteric fistula were reviewed by a single observer for the presence of a potentially predictive finding of fistulization, the aortic bulge sign. These previous images were then combined with age and sex matched controls into a case bank. Eight radiology residents and staff were instructed in observing the aortic bulge sign. These observers then reviewed the case bank in a blinded analysis to determine the interobserver reliability of this finding.

Results: Fourteen cases of aortoenteric were identified. The average patient age was 70.71 years with a male-to-female ratio of 11:3. Eleven patients had previous computed tomography images available for review. With blinded analysis by multiple observers, the aortic bulge sign was identified with greater than 80% agreement in six of 11 cases (66.67%). Fleiss' kappa was calculated at k = 0.60 (95% confidence interval 0.50-0.69), corresponding to moderate-to-substantial interobserver agreement.

Conclusions: The aortic bulge sign has been retrospectively identified as a promising computed tomography finding of eventual aortoenteric fistula prior to acute presentation. Further study is required to determine the diagnostic value of this sign.

Keywords: Abdominal aortic aneurysm; Aorta; Aortoduodenal fistula; Aortoenteric fistula; Endovascular aortic repair; Graft infection.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Aorta / diagnostic imaging*
  • Aorta / pathology*
  • Aortic Diseases / diagnostic imaging*
  • Aortic Diseases / pathology
  • Digestive System Fistula / diagnostic imaging*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Reproducibility of Results
  • Retrospective Studies
  • Tomography, X-Ray Computed / methods*
  • Vascular Fistula / diagnostic imaging*