Factors affecting adherence and patient satisfaction with treatment: a cross-sectional study of 500 patients with acne vulgaris

J Dermatolog Treat. 2021 Feb;32(1):64-69. doi: 10.1080/09546634.2019.1618434. Epub 2019 May 28.

Abstract

Background: Acne Vulgaris is a chronic inflammatory disease that requires long-term treatment. Adherence to treatment is a problem in chronic diseases and may affect treatment outcomes.Objective: We aim to investigate treatment adherence and satisfaction of patients with acne and identify independent factors that affect them.Methods: Five hundred patients with acne were included in this cross-sectional study. Demographic and clinical characteristics of the patients were recorded. Severity of acne was assessed using the Investigator Global Assessment (IGA) scale, and a five-point Likert scale was used to assess patients' satisfaction and adherence.Results: Adherence to treatment was poor in 64.4% of the patients. Multivariate logistic regression analysis showed that using oral isotretinoin (OR: 4.1, 95% CI 2.44-6.92, p < .001) and satisfaction with treatment (OR: 2.1, 95% CI 1.31-3.43, p = .002) were independent factors that affect adherence in patients. 51.8% of the patients were satisfied with their treatments and treatment satisfaction was higher in females (OR: 2.2, 95% CI 1.3-3.8, p = .004) and patients using oral isotretinoin (OR: 14.8, 95% CI 9.4-23.2, p < .001).Conclusions: Treatment adherence is poor among patients with acne. Identifying the factor that affects adherence may help the dermatologist recognize non-adherent patients and develop strategies to improve adherence.

Keywords: Acne vulgaris; adherence; satisfaction; treatment.

MeSH terms

  • Acne Vulgaris / drug therapy
  • Acne Vulgaris / psychology*
  • Administration, Oral
  • Adolescent
  • Adult
  • Cross-Sectional Studies
  • Female
  • Humans
  • Isotretinoin / therapeutic use
  • Logistic Models
  • Male
  • Odds Ratio
  • Patient Satisfaction*
  • Sex Factors
  • Treatment Adherence and Compliance*
  • Young Adult

Substances

  • Isotretinoin