Exploiting Allelic Variation in CD8+ T Cells

Anthonie J Zwijnenburg; Carmen Gerlach

doi:10.1016/j.immuni.2019.05.001

Exploiting Allelic Variation in CD8⁺ T Cells

Immunity. 2019 May 21;50(5):1119-1121. doi: 10.1016/j.immuni.2019.05.001.

Authors

Anthonie J Zwijnenburg¹, Carmen Gerlach²

Affiliations

¹ Department of Medicine Solna, Division of Rheumatology, Karolinska Institutet, 171 76 Stockholm, Sweden; POC Rheuma/Hud/Gastro Infection and Inflammation, Karolinska University Hospital Solna, 171 76 Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital Solna, 171 76 Stockholm, Sweden.
² Department of Medicine Solna, Division of Rheumatology, Karolinska Institutet, 171 76 Stockholm, Sweden; POC Rheuma/Hud/Gastro Infection and Inflammation, Karolinska University Hospital Solna, 171 76 Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital Solna, 171 76 Stockholm, Sweden. Electronic address: carmen.gerlach@ki.se.

PMID: 31117005
DOI: 10.1016/j.immuni.2019.05.001

Abstract

In this issue of Immunity, van der Veeken et al. (2019) leverage genetic variation between mouse strains to assess epigenetic and transcriptional regulation dynamics in CD8⁺ T cells responding to acute infection.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Animals
CD8-Positive T-Lymphocytes*
Epigenesis, Genetic
Epigenomics
Gene Expression Regulation*
Genetic Variation
Mice