Background: Post-operative paediatric cerebellar mutism syndrome is a well-recognized complication following posterior fossa tumour resection in children. Over the past few decades, imaging has played an important role in understanding this disorder.
Aim: This review article aims to focus on the disorder from a radiological perspective, summarizing the salient radiological evidence related to the anatomical structures, pathophysiology, and risk factors related to this disorder.
Conclusion: Radiological studies have been integral to the improved understanding of this condition. Future large multicentre studies and quantitative analysis techniques will be vital in further refinement of our understanding of this complex condition.
Keywords: Anatomical substrates; Cerebellar mutism syndrome; Pathophysiology; Post-operative paediatric cerebellar mutism syndrome; Posterior fossa syndrome; Radiology.