The Worst from Both Worlds: cHCC-ICC

Marco Seehawer; Luana D'Artista; Lars Zender

doi:10.1016/j.ccell.2019.05.008

The Worst from Both Worlds: cHCC-ICC

Cancer Cell. 2019 Jun 10;35(6):823-824. doi: 10.1016/j.ccell.2019.05.008.

Authors

Marco Seehawer¹, Luana D'Artista¹, Lars Zender²

Affiliations

¹ Department of Medical Oncology & Pneumology, University Hospital Tübingen, 72076 Tübingen, Germany.
² Department of Medical Oncology & Pneumology, University Hospital Tübingen, 72076 Tübingen, Germany; German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg 69120, Germany. Electronic address: lars.zender@med.uni-tuebingen.de.

PMID: 31185207
DOI: 10.1016/j.ccell.2019.05.008

Abstract

Prognosis of combined hepatocellular carcinoma-intrahepatic cholangiocarcinoma, a type of primary liver cancer comprising areas with HCC and ICC histopathology, is dismal, and it is unclear if such tumors develop clonally and how they should be treated. In this issue of Cancer Cell, Xue et al. (2019) provide answers to these questions.

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MeSH terms

Bile Duct Neoplasms*
Carcinoma, Hepatocellular*
Cholangiocarcinoma*
Genomics
Humans
Liver Neoplasms*
Prognosis
Transcriptome