Cutaneous involvement of polymorphic post-transplant lymphoproliferative disorder in a child after liver transplantation

Pediatr Dermatol. 2019 Sep;36(5):681-685. doi: 10.1111/pde.13903. Epub 2019 Jun 18.

Abstract

Post-transplantation lymphoproliferative disorder (PTLD) is one of the most common de novo malignancies in patients who receive immunosuppressive therapy after solid organ transplantation. We report a case of a 5-year-old girl who presented with indurated violaceous skin nodules 3.5 years post-liver transplantation, diagnosed as polymorphic PTLD, also involving Waldeyer's ring, spleen, and multiple lymph nodes. Through reduction of immunosuppression, most of the lesions resolved and the liver allograft was preserved.

Keywords: child; liver transplantation; lymphoproliferative disorders.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Female
  • Humans
  • Immunosuppression Therapy / adverse effects*
  • Liver Transplantation / adverse effects*
  • Lymphoproliferative Disorders / diagnosis
  • Lymphoproliferative Disorders / etiology*
  • Postoperative Complications / diagnosis
  • Postoperative Complications / etiology*
  • Skin Diseases / diagnosis*
  • Skin Diseases / etiology*