Compartments in the Ring

Mol Cell. 2019 Jul 25;75(2):201-203. doi: 10.1016/j.molcel.2019.07.002.

Abstract

Sister chromatid cohesion has been thought to be mediated by DNA entrapment within the large cohesin ring. Vazquez Nunez et al. and Chapard et al. now show that the ring is divided up into two sub-compartments, with implications for how these chromosomal organizers entrap DNA.

Publication types

  • Comment

MeSH terms

  • Cell Cycle Proteins / genetics
  • Chromatids*
  • Chromosomal Proteins, Non-Histone / genetics
  • Cohesins
  • DNA
  • Saccharomyces cerevisiae Proteins / genetics*

Substances

  • Cell Cycle Proteins
  • Chromosomal Proteins, Non-Histone
  • Saccharomyces cerevisiae Proteins
  • DNA