Neurologic complications of melanoma

Cancer. 2020 Feb 1;126(3):477-486. doi: 10.1002/cncr.32619. Epub 2019 Nov 14.

Abstract

Neurologic complications are common in patients with melanoma and are often associated with a poor prognosis. In an era with new, effective treatments, patients are living longer, and this has resulted in an increase in complications of both the disease and the therapy. A multidisciplinary approach to neurologic complications in patients with melanoma, with involvement from medical oncology, neuro-oncology, radiation oncology, and often neurosurgery, is necessary. In this review, neurologic complications of melanoma, including clinical implications and treatment strategies, are described.

Keywords: melanoma; neuro-oncology; neurologic.

Publication types

  • Review

MeSH terms

  • Female
  • Humans
  • Male
  • Melanoma / complications
  • Melanoma / diagnosis
  • Melanoma / epidemiology*
  • Melanoma / therapy
  • Nervous System Diseases / diagnosis
  • Nervous System Diseases / epidemiology*
  • Nervous System Diseases / etiology
  • Nervous System Diseases / therapy
  • Neuroimaging / methods
  • Neurosurgery / trends
  • Prognosis*
  • Radiation Oncology / trends
  • Treatment Outcome