Could PD-1/PDL1 immune checkpoints be linked to HLA signature?

Immunotherapy. 2019 Dec;11(18):1523-1526. doi: 10.2217/imt-2019-0160. Epub 2019 Dec 9.
No abstract available

Keywords: HLA alleles; PD-1/PDL-1-blockade; irAEs; outcome.

Publication types

  • Editorial

MeSH terms

  • Antibodies, Monoclonal / adverse effects
  • Antibodies, Monoclonal / therapeutic use*
  • B7-H1 Antigen / antagonists & inhibitors*
  • B7-H1 Antigen / immunology
  • Biomarkers
  • Drug-Related Side Effects and Adverse Reactions / immunology
  • HLA Antigens / genetics*
  • HLA Antigens / immunology
  • Haplotypes
  • Humans
  • Immunotherapy / adverse effects
  • Neoplasms / immunology
  • Neoplasms / therapy*
  • Programmed Cell Death 1 Receptor / antagonists & inhibitors*
  • Programmed Cell Death 1 Receptor / immunology

Substances

  • Antibodies, Monoclonal
  • B7-H1 Antigen
  • Biomarkers
  • HLA Antigens
  • Programmed Cell Death 1 Receptor