Crohn's disease in Israeli Jews of Ethiopian heritage-a case series

Int J Colorectal Dis. 2020 Mar;35(3):565-567. doi: 10.1007/s00384-019-03474-0. Epub 2019 Dec 23.

Abstract

Introduction: There is a paucity of information on the prevalence of Crohn's disease (CD) in patients of African heritage. Israel is home to approximately 144,100 Jews of Ethiopian heritage. We present an audit of six patients of Ethiopian heritage in our surgical IBD clinic.

Report: Six patients are presented. All but one was born in Ethiopia. The age of diagnosis ranged from 19 to 43. Of those who immigrated to Israel, all were diagnosed with Crohn's 10 years or more after immigration. All patients required surgery. Nearly all patients had disease of the terminal ileum (5/6), and many had perianal disease (4/6).

Discussion: This series indicates the existence of Crohn's disease in a population previously unassociated with this disease. These patients demonstrate that like all other patients with Crohn's disease, many will require surgery for either intestinal or perianal disease. Patients of Ethiopian descent with clinical symptoms and signs suspicious of Crohn's should be referred for diagnostic testing.

Keywords: Case series; Crohn’s disease; Epidemiology; Ethiopia.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Crohn Disease / epidemiology*
  • Ethiopia / epidemiology
  • Female
  • Humans
  • Israel / epidemiology
  • Jews*
  • Male
  • Middle Aged