Objective: To investigate the prevalence characters of peripheral artery disease (PAD) and associated factors among people aged 35 and above in Beijing. Methods: This was a cross-sectional study. A total of 5 208 community-based individuals aged equal and above 35 in Beijing were chosen with stratified multistage random sampling method. Structure questionnaire was used to collected the information of demographic factors, habits and chronic disease history. Ankle brachial blood pressure was detected and ankle brachial index (ABI) was calculated. ABI was used to diagnose PAD (ABI≤0.90). Based on the 2010 Beijing Municipal Population Census, the age-and gender-specific weight-adjusted sample was acquired to estimate the prevalence of PAD and corresponding 95% confidence intervals (CI). Multivariate logistic regression analysis was performed to estimate the associated factors of PAD. Results: The age-and sex-standardized prevalence of PAD was 3.84% (200/5 208, 95%CI 3.32%-4.36%). There was no significant difference between male and female (3.83%(102/2 664, 95%CI 3.10%-4.56%) vs. 3.85% (98/2 544, 95%CI 3.10%-4.60%), P=0.965). The prevalence of PAD in urban was higher than that in rural (4.34% (163/3 755, 95%CI 3.69%-4.99%) vs. 2.55% (37/1 453, 95%CI 1.74%-3.36%), P=0.001). Furthermore, the prevalence of PAD increased with age (P(trend)<0.01), and the difference between genders did not change with ageing (all P>0.05). In addition, age (OR=1.03, 95%CI 1.01-1.04), urban (OR=1.52, 95%CI 1.08-2.12), smoking (OR=1.83, 95%CI 1.29-2.59), hypertension (OR=1.61, 95%CI 1.17-2.22) and diabetes (OR=1.44, 95%CI 1.08-1.93) were related with increased risk of PAD in logistic regression analysis models. Conclusions: The prevalence of PAD increases with age in Beijing and there are significant difference between urban and rural on prevalence of PAD. Age, urban, smoking, hypertension and diabetes are related with increased risk of PAD.
目的： 调查北京地区≥35岁人群外周动脉疾病（PAD）的患病率特点及相关影响因素。 方法： 该研究为横断面调查，采用分层多阶段随机抽样方法抽取北京地区≥35岁者，共5 208人。采用问卷调查的方式，收集纳入人群的人口学资料、生活习惯和疾病史；测量所有被调查者的臂踝血压，并计算踝臂指数（ABI），以ABI诊断PAD（ABI≤0.90）。按照2010年全国第6次人口普查北京市人口年龄和性别构成比确定权重后，计算PAD的标化患病率及其95%CI，并采用多因素logistic回归分析探讨PAD的相关因素。 结果： 经年龄和性别标化后，PAD患病率为3.84%（200/5 208，95%CI 3.32%~4.36%），其中男性和女性分别为3.83%（102/2 664，95%CI 3.10%~4.56%）和3.85%（98/2 544，95%CI 3.10%~4.60%），差异无统计学意义（P=0.965）；城市人群PAD患病率高于农村人群[4.34%（163/3 755，95%CI 3.69%~4.99%）比2.55%（37/1 453，95%CI 1.74%~3.36%），P=0.001]。PAD的患病率随年龄增加而升高（趋势卡方检验P<0.01），各年龄组男女患病率差异无统计学意义（P均>0.05）。多因素logistic回归分析结果显示，年龄（OR=1.03，95%CI 1.01~1.04）、地区（城市）（OR=1.52，95%CI 1.08~2.12）、吸烟（OR=1.83，95%CI 1.29~2.59）、高血压（OR=1.61，95%CI 1.17~2.22）、糖尿病（OR=1.44，95%CI 1.08~1.93）与PAD患病风险正相关。 结论： 北京地区PAD的患病率呈现随年龄增长而升高的趋势，城市人群患病率高于农村，年龄、地区（城市）、吸烟、高血压、糖尿病与PAD患病有关。.
Keywords: Ankle brachial index; Peripheral vascular diseases; Prevalence.