Progress in the development of biosensors has dramatically improved analytical techniques. Biosensors have advantages over more conventional analytical techniques arising from attributes such as straightforward analyses, higher throughput, miniaturization, smaller sample input, and lower cost. Microring optical resonators have emerged in the area of optical sensors as an exceptional choice due to their sensitivity, ease of fabrication, multiplexity capability and label-free detection. In this paper, the sensing principle of these sensors is described. In addition, we summarize and highlight their most recent and relevant applications in environmental and clinical detection analysis.