Data on the influence of inorganic clays to improve mechanical and healing properties of antibacterial Gellan gum-Manuka honey hydrogels

Maria A Bonifacio; Andrea Cochis; Stefania Cometa; Annachiara Scalzone; Piergiorgio Gentile; Giuseppe Procino; Serena Milano; Alessandro C Scalia; Lia Rimondini; Elvira De Giglio

doi:10.1016/j.dib.2019.105096

Data on the influence of inorganic clays to improve mechanical and healing properties of antibacterial Gellan gum-Manuka honey hydrogels

Data Brief. 2020 Jan 7:28:105096. doi: 10.1016/j.dib.2019.105096. eCollection 2020 Feb.

Affiliations

¹ Department of Chemistry, University of Bari "Aldo Moro", via E. Orabona 4, Bari, 70126, Italy.
² Department of Health Sciences, University of Piemonte Orientale UPO, Center for Translational Research on Autoimmune and Allergic Diseases (CAAD), c.so Trieste 15/A, Novara, 28100, Italy.
³ Jaber Innovation s.r.l., via Calcutta 8, Rome, 00144, Italy.
⁴ School of Engineering, Newcastle University, Stephenson Building, Claremont Road, Newcastle upon Tyne, NE1 7RU, UK.
⁵ Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari "Aldo Moro", via E. Orabona 4, Bari, 70126, Italy.

Abstract

This work contains original data supporting our research paper "Advances in cartilage repair: the influence of inorganic clays to improve mechanical and healing properties of antibacterial Gellan gum-Manuka honey hydrogels", by Maria A. Bonifacio, Andrea Cochis, Stefania Cometa, Annachiara Scalzone, Piergiorgio Gentile, Giuseppe Procino, Serena Milano, Alessandro C. Scalia, Lia Rimondini, Elvira De Giglio [1]. The main paper describes how four different clays (i.e., mesoporous silica, bentonite and halloysite nanotubes, coded as MS, BE and HNT) as cheap, abundant and versatile feed materials can be used for the preparation of highly performant hydrogels as cartilage substitutes, based on Gellan Gum (GG) and Manuka Honey (MH). Here the composites were further examined by means of Thermogravimetric Analysis (TGA), histological analysis (Alcian blue and Safranin-O) and static compression tests. This set of data strengthens the evidence that these hydrogels possess biological and physicochemical characteristics suitable for their application as reinforcing inorganic fillers in composite materials designed for cartilage regeneration.

Keywords: Composite hydrogels; Cytocompatibility; Gellan gum; Inorganic clays; Mechanical behaviour; Swelling; Thermal characterization.