Iatrogenic Decompensated Heart Failure

Curr Heart Fail Rep. 2020 Apr;17(2):21-27. doi: 10.1007/s11897-020-00452-4.

Abstract

Purpose of review: To provide an overview of the potential iatrogenic causes of acute decompensated heart failure (AHF) and an evidence-based management strategy to address this.

Recent findings: As the heart failure (HF) population continues to age and become burdened with greater comorbidities and polypharmacy, patients become more susceptible to the iatrogenic precipitants of HF. The following clinical scenarios are familiar to clinicians, but the sequelae to AHF are often unanticipated: HF medications withdrawn during an intercurrent illness and not restarted, cardiotoxic therapy prescribed for cancer without timely and regular monitoring of left ventricular function, excessive intravenous fluids administered for sepsis or postoperatively, a blood transfusion volume not adjusted for body weight, iatrogenic anaemia that goes unnoticed or an inappropriate type of pacemaker implanted in a patient with underlying left ventricular systolic dysfunction. Iatrogenic decompensated HF is a phenomenon that is infrequently documented in the literature but increasingly confronted by clinicians of all specialties. It is associated with a high mortality and morbidity rate. By having greater awareness of these triggers, iatrogenic AHF should be one that is prevented rather than managed when it occurs.

Keywords: Decompensated heart failure; Fluid management; High-output heart failure; Iatrogenic; Pacemaker; Pharmacotherapy.

Publication types

  • Review

MeSH terms

  • Acute Disease
  • Disease Progression
  • Global Health
  • Heart Failure / epidemiology
  • Heart Failure / etiology*
  • Heart Failure / physiopathology
  • Humans
  • Iatrogenic Disease / epidemiology*
  • Incidence
  • Time Factors
  • Ventricular Function, Left / physiology*