Effect of positive urine fentanyl screen on attitudes toward heroin use

Drug Alcohol Depend. 2020 Apr 1:209:107934. doi: 10.1016/j.drugalcdep.2020.107934. Epub 2020 Feb 20.

Abstract

Background: It is unknown if targeted risk reduction counseling in the health care setting, after documented exposure to fentanyl, can affect behavior change to reduce risks and increase utilization of evidence-based overdose prevention strategies.

Methods: We conducted a retrospective analysis of results (7/2018-6/2019) from questionnaire-facilitated counseling by recovery coaches in the emergency department (ED) and primary care settings following disclosure of a urine toxicology positive for fentanyl.

Results: Seventy-five percent of N = 101 respondents were neither aware of nor expecting fentanyl in their substances of use. Fifty-three (70 %) of those initially unaware answered that learning about exposure to and the risks from fentanyl changed their thoughts about reducing or abstaining from use. A greater proportion of patients seen in the ED expressed desire to stop or reduce opioid use as compared to ambulatory clinic patients (91 % vs. 46 %, p < 0.001). Of those not already engaged in treatment, 18 % and 15 % were interested in medication and behavioural health treatment, respectively, and each of them indicated a change in thought based on the counseling. Forty-five percent of individuals not yet receiving naloxone endorsed interest in receiving it, and 22 % of all respondents were somewhat or very interested in access to safe consumption sites.

Conclusion: This study suggests a novel clinical utility in toxicology screens to inform behavior in the setting of illicit fentanyl exposure. In addition to linkages to evidence-based treatment, linkages to harm-mitigating strategies associated with ongoing substance use may be critical to a comprehensive overdose prevention strategy in the clinical setting.

Keywords: Fentanyl, harm reduction counseling; Naloxone; Opioid use disorder; Safe consumption sites; Toxicology.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Analgesics, Opioid / adverse effects
  • Analgesics, Opioid / urine
  • Drug Overdose / prevention & control
  • Drug Overdose / psychology
  • Drug Overdose / urine
  • Emergency Service, Hospital / trends
  • Female
  • Fentanyl / analysis
  • Fentanyl / urine*
  • Health Knowledge, Attitudes, Practice*
  • Heroin / analysis
  • Heroin / urine
  • Heroin Dependence / psychology*
  • Heroin Dependence / therapy
  • Heroin Dependence / urine*
  • Humans
  • Male
  • Middle Aged
  • Naloxone / therapeutic use
  • Opioid-Related Disorders / prevention & control
  • Opioid-Related Disorders / psychology
  • Opioid-Related Disorders / urine
  • Retrospective Studies
  • Risk Reduction Behavior
  • Surveys and Questionnaires
  • Young Adult

Substances

  • Analgesics, Opioid
  • Naloxone
  • Heroin
  • Fentanyl