Capturing and monitoring global differences in untreated and treated end-stage kidney disease, kidney replacement therapy modality, and outcomes

Roberto Pecoits-Filho; Ikechi G Okpechi; Jo-Ann Donner; David C H Harris; Harith M Aljubori; Aminu K Bello; Ezequiel Bellorin-Font; Fergus J Caskey; Allan Collins; Alfonso M Cueto-Manzano; John Feehally; Bak Leong Goh; Kitty J Jager; Masaomi Nangaku; Muhibur Rahman; Manisha Sahay; Abdulkarim Saleh; Laura Sola; Rumeyza Turan Kazancioglu; Rachael C Walker; Robert Walker; Qiang Yao; Xueqing Yu; Ming-Hui Zhao; David W Johnson

doi:10.1016/j.kisu.2019.11.001

Capturing and monitoring global differences in untreated and treated end-stage kidney disease, kidney replacement therapy modality, and outcomes

Kidney Int Suppl (2011). 2020 Mar;10(1):e3-e9. doi: 10.1016/j.kisu.2019.11.001. Epub 2020 Feb 19.

Authors

Roberto Pecoits-Filho^{1

2}, Ikechi G Okpechi^{3

4}, Jo-Ann Donner⁵, David C H Harris⁶, Harith M Aljubori⁷, Aminu K Bello⁸, Ezequiel Bellorin-Font⁹, Fergus J Caskey^{10

11

12}, Allan Collins^{13

14}, Alfonso M Cueto-Manzano¹⁵, John Feehally¹⁶, Bak Leong Goh¹⁷, Kitty J Jager¹⁸, Masaomi Nangaku¹⁹, Muhibur Rahman²⁰, Manisha Sahay²¹, Abdulkarim Saleh²², Laura Sola²³, Rumeyza Turan Kazancioglu^{24

25}, Rachael C Walker^{24

25

26}, Robert Walker²⁷, Qiang Yao²⁸, Xueqing Yu^{29

30}, Ming-Hui Zhao^{31

32

33

34}, David W Johnson^{35

36

37}

Affiliations

¹ School of Medicine, Pontificia Universidade Catolica do Paraná, Curitiba, Brazil.
² Arbor Research Collaborative for Health, Ann Arbor, Michigan, USA.
³ Division of Nephrology and Hypertension, University of Cape Town, Cape Town, South Africa.
⁴ Kidney and Hypertension Research Unit, University of Cape Town, Cape Town, South Africa.
⁵ International Society of Nephrology, Brussels, Belgium.
⁶ Centre for Transplantation and Renal Research, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia.
⁷ Nephrology Department, Alqassimi Hospital, Sharjah, United Arab Emirates.
⁸ Division of Nephrology and Immunity, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
⁹ Division of Nephology and Hypertension, Department of Medicine, Saint Louis University, Saint Louis, Missouri, USA.
¹⁰ UK Renal Registry, Learning and Research, Southmead Hospital, Bristol, UK.
¹¹ Population Health Sciences, University of Bristol, Bristol, UK.
¹² The Richard Bright Renal Unit, Southmead Hospital, North Bristol National Health Service Trust, Bristol, UK.
¹³ NxStage Medical, Inc., Lawrence, Massachusetts, USA.
¹⁴ Department of Medicine, University of Minnesota School of Medicine, Minneapolis, Minnesota, USA.
¹⁵ Unidad de Investigación Médica en Enfermedades Renales, Hospital de Especialidades, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, México.
¹⁶ University of Leicester, Leicester, UK.
¹⁷ Department of Nephrology and Clinical Research Centre, Hospital Serdang, Jalan Puchong, Kajang, Selangor, Malaysia.
¹⁸ European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry, Department of Medical Informatics, Academic Medical Center, Amsterdam Public Health Research Institute, University of Amsterdam, Amsterdam, the Netherlands.
¹⁹ Division of Nephrology, The University of Tokyo School of Medicine, Hongo, Japan.
²⁰ Department of Nephrology, Sir Salimullah Medical College and Mitford Hospital, Dhaka, Bangladesh.
²¹ Department of Nephrology, Osmania Medical College and General Hospital, Hyderabad, Telangana, India.
²² Department of Nephrology, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates.
²³ Dialysis Unit, Centro Asistencial del Sindicato Médico del Uruguay Institución de Asistencia Médica Privada de Profesionales Sin Fines de lucro, Montevideo, Uruguay.
²⁴ Division of Nephrology, Bezmialem Vakif University, Istanbul, Turkey.
²⁵ Walker, School of Nursing, Eastern Institute of Technology, Napier, New Zealand.
²⁶ Renal Department, Hawke's Bay District Health Board, Hastings, New Zealand.
²⁷ Department of Medicine, University of Otago, Dunedin, New Zealand.
²⁸ Medical Affairs, Baxter Healthcare, Guangzhou, China.
²⁹ Division of Nephrology, Guangdong Provincial People's School of Medicine, South China University of Technology, Guangzhou, China.
³⁰ Key Laboratory of Nephrology, Ministry of Health, Guangzhou, Guangdong, China.
³¹ Renal Division, Department of Medicine, Peking University First Hospital, Beijing, China.
³² Key Laboratory of Renal Disease, Ministry of Health of China, Beijing, China.
³³ Key Laboratory of Chronic Kidney Disease Prevention and Treatment, Ministry of Education of China, Beijing, China.
³⁴ Peking-Tsinghua Center for Life Sciences, Beijing, China.
³⁵ Centre for Kidney Disease Research, University of Queensland, Brisbane, Australia.
³⁶ Translational Research Institute, Brisbane, Australia.
³⁷ Metro South and Ipswich Nephrology and Transplant Services, Princess Alexandra Hospital, Brisbane, Australia.

Abstract

A large gap between the number of people with end-stage kidney disease (ESKD) who received kidney replacement therapy (KRT) and those who needed it has been recently identified, and it is estimated that approximately one-half to three-quarters of all people with ESKD in the world may have died prematurely because they could not receive KRT. This estimate is aligned with a previous report that estimated that >3 million people in the world died each year because they could not access KRT. This review discusses the reasons for the differences in treated and untreated ESKD and KRT modalities and outcomes and presents strategies to close the global KRT gap by establishing robust health information systems to guide resource allocation to areas of need, inform KRT service planning, enable policy development, and monitor KRT health outcomes.

Keywords: end-stage kidney disease; global health; health information systems; health services accessibility; kidney replacement therapy; registries.

Publication types

Review