Transchondral access for irreversible electroporation of hepatocellular carcinoma

Mohamed Elboraey; Zlatko Devcic; Andrew R Lewis; Charles A Ritchie; Gregory T Frey; Ricardo Paz-Fumagalli; J Mark McKinney; Beau B Toskich

doi:10.1016/j.radcr.2020.01.032

Transchondral access for irreversible electroporation of hepatocellular carcinoma

Radiol Case Rep. 2020 Mar 5;15(5):531-533. doi: 10.1016/j.radcr.2020.01.032. eCollection 2020 May.

Authors

Mohamed Elboraey¹, Zlatko Devcic¹, Andrew R Lewis¹, Charles A Ritchie¹, Gregory T Frey¹, Ricardo Paz-Fumagalli¹, J Mark McKinney¹, Beau B Toskich¹

Affiliation

¹ Mayo Clinic Florida, 4500 San Pablo Street, Jacksonville 32224, FL, USA.

Abstract

Ablative treatment for hepatocellular carcinoma is standard of care in selected settings and is endorsed by international societal guidelines. Centrally located hepatocellular carcinoma are difficult to treat due to their proximity to vasculature and central bile ducts. Irreversible electroporation is a nonthermal ablation modality that has been shown to preserve the extracellular matrix and is less likely to damage structures such as bile ducts and is not susceptible to vascular heat sink. Successful irreversible electroporation requires the parallel placement of probes which can be prevented by ribs or the sternum. This case report describes the use of the coaxial bone biopsy system to enable transchondral access and facilitate parallel placement of probes during irreversible electroporation IRE for the treatment of hepatocellular carcinoma.

Keywords: Bonopty needle device; Hepatocellular carcinoma; Irreversible electroporation; Transchondral access.

Publication types

Case Reports