Anaplastic multiple myeloma resembling dysplastic megakaryocytes

Wei Xie; Guilin Tang; Shaoying Li; C Cameron Yin; Jie Xu

doi:10.1002/ccr3.2425

Anaplastic multiple myeloma resembling dysplastic megakaryocytes

Clin Case Rep. 2019 Sep 30;8(3):568-569. doi: 10.1002/ccr3.2425. eCollection 2020 Mar.

Authors

Wei Xie¹, Guilin Tang¹, Shaoying Li¹, C Cameron Yin¹, Jie Xu¹

Affiliation

¹ Department of Hematopathology The University of Texas MD Anderson Cancer Center Houston TX USA.

Abstract

Anaplastic multiple myeloma (AMM) is a very rare morphologic variant of multiple myeloma with extremely poor prognosis. The anaplastic morphology of AMM may pose a diagnostic challenge. A thorough workup is critical in reaching the correct diagnosis.

Keywords: IGH/CCND1 rearrangement; TP53 loss of function; anaplastic multiple myeloma; dysplastic megakaryocytes.