Hunting Cells for Gentle Liberation

Günter Mayer; Tjasa Legen; Tejal Patwari; Anna Maria Weber

doi:10.1016/j.chembiol.2020.02.006

Hunting Cells for Gentle Liberation

Cell Chem Biol. 2020 Mar 19;27(3):257-258. doi: 10.1016/j.chembiol.2020.02.006.

[Article in Albanian, English]

Authors

Günter Mayer¹, Tjasa Legen², Tejal Patwari³, Anna Maria Weber²

Affiliations

¹ Life and Medical Sciences Institute, University of Bonn, Gerhard-Domagk-Str. 1, 53121 Bonn, Germany; Center of Aptamer Research and Development, University of Bonn, Gerhard-Domagk-Str. 1, 53121 Bonn, Germany. Electronic address: gmayer@uni-bonn.de.
² Life and Medical Sciences Institute, University of Bonn, Gerhard-Domagk-Str. 1, 53121 Bonn, Germany; Center of Aptamer Research and Development, University of Bonn, Gerhard-Domagk-Str. 1, 53121 Bonn, Germany.
³ Life and Medical Sciences Institute, University of Bonn, Gerhard-Domagk-Str. 1, 53121 Bonn, Germany.

PMID: 32200913
DOI: 10.1016/j.chembiol.2020.02.006

Abstract

In a recent issue of Cell Chemical Biology, Gray et al. (2020) report an aptamer-based method to reversibly label and isolate EGF receptor-expressing cells from heterogeneous mixtures by cell sorting approaches. Subsequent treatment using complementary oligonucleotides restores full functionality of EGF receptors, highlighting the superiority of this method to antibody-based sorting.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Cell Movement
Ligands
Oligonucleotides*
Protein Transport

Substances

Ligands
Oligonucleotides