Management of Sinusitis in the Cystic Fibrosis Patient

Somtochi Okafor; Kathleen M Kelly; Ashleigh A Halderman

doi:10.1016/j.iac.2019.12.008

Management of Sinusitis in the Cystic Fibrosis Patient

Immunol Allergy Clin North Am. 2020 May;40(2):371-383. doi: 10.1016/j.iac.2019.12.008. Epub 2020 Jan 22.

Authors

Somtochi Okafor¹, Kathleen M Kelly¹, Ashleigh A Halderman²

Affiliations

¹ Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, 2001 Inwood Road, Dallas, TX 75390, USA.
² Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, 2001 Inwood Road, Dallas, TX 75390, USA. Electronic address: ashleigh.halderman@utsouthwestern.edu.

PMID: 32278458
DOI: 10.1016/j.iac.2019.12.008

Abstract

Chronic rhinosinusitis (CRS) is present in up to 100% of patients with cystic fibrosis (CF). CF-associated CRS is particularly recalcitrant, and sinus disease can have important implications in the health of the lower airways and overall quality of life in these patients. Both medical and surgical management play important roles in treating CF-associated CRS, but guidelines are lacking. This review summarizes the current literature on both medical and surgical management of this disease to provide an up-to-date analysis and recommendations on the treatment of CF-associated CRS.

Keywords: Chronic rhinosinusitis; Cystic fibrosis; Endoscopic sinus surgery; Medical management; Sinusitis.

Publication types

Review

MeSH terms

Chronic Disease
Cystic Fibrosis / complications
Cystic Fibrosis / diagnosis*
Cystic Fibrosis / therapy
Endoscopy
Humans
Practice Guidelines as Topic
Quality of Life
Rhinitis / complications
Rhinitis / diagnosis*
Rhinitis / therapy
Sinusitis / complications
Sinusitis / diagnosis*
Sinusitis / therapy