Helicobacter pylori (Hp) is a Gram-negative microaerobic bacterium, which is parasitic on gastric mucosa and is associated with the pathogenesis of chronic gastritis, gastric ulcer, gastric cancer and other gastric diseases. Meanwhile, the Hp infection is related with pregnancy-related diseases, pregnancy outcomes, and the health status of offspring, such as infertility, premature delivery, abortion, Hp infection of newborn and neural tube defects. Hp infection is also related to hyperemesis of pregnancy, preeclampsia, gestational diabetes mellitus, iron deficiency anemia, idiopathic thrombocytopenic purpura. It has been suggested that early diagnosis and eradication of Hp and standardized the anti-Hp treatment will benefit pregnant women and their offspring.
幽门螺杆菌(Helicobacter pylori，Hp)是一种寄生于胃黏膜组织的革兰氏阴性微需氧细菌，与慢性胃炎、胃溃疡、胃肿瘤等多种胃部疾病的发生相关。同时，Hp感染与妊娠相关疾病、妊娠结局及子代的健康状况(如不孕、早产、流产及新生儿Hp感染、神经管缺陷等)有关；还与妊娠剧吐、先兆子痫、妊娠期糖尿病、缺铁性贫血、特发性血小板减少性紫癜等疾病的发生存在一定的关联。早期诊断、根除Hp和规范化的抗Hp治疗可在一定程度上使孕妇及子代获益。.
Keywords: Helicobacter pylori; adverse pregnancy outcomes; pregnancy-related diseases; pregnant women.