A Review of Mullerian Anomalies and Their Urologic Associations

Urology. 2021 May:151:98-106. doi: 10.1016/j.urology.2020.04.088. Epub 2020 May 6.

Abstract

Structural anomalies of the female reproductive tract, known as Mullerian anomalies, can occur in isolation or in association with anomalies of other organ systems. Due to shared embryology, the most common association in up to 40% of patients is with renal, ureteral, and bladder anomalies. Affected girls can have a wide range of genitourinary symptoms with urologists playing an integral role in their diagnosis and treatment. To facilitate the recognition and management of these conditions, we provide a review of Mullerian anomalies including the embryology, classifications, syndromes, evaluation, and treatments with attention to their urologic applicability.

Publication types

  • Review

MeSH terms

  • 46, XX Disorders of Sex Development / complications
  • Anorectal Malformations / complications
  • Anus, Imperforate / complications
  • Congenital Abnormalities
  • Female
  • Genitalia, Female / embryology
  • Hernia, Umbilical / complications
  • Humans
  • Mullerian Ducts / abnormalities*
  • Scoliosis / complications
  • Urinary Tract / embryology
  • Urogenital Abnormalities / classification
  • Urogenital Abnormalities / complications*
  • Urogenital Abnormalities / diagnosis
  • Urogenital Abnormalities / therapy

Supplementary concepts

  • Mullerian aplasia
  • Omphalocele exstrophy imperforate anus