Redirecting E2F1 to TA-p73 improves cancer therapy through apoptotic induction

DNA Repair (Amst). 2020 Jun:90:102858. doi: 10.1016/j.dnarep.2020.102858. Epub 2020 Apr 28.

Author

Mohammed El Dika¹

Affiliation

¹ Institut Curie, PSL Research University, CNRS, UMR3348, Orsay, France; Paris Sud University, Paris-Saclay University, CNRS, UMR3348, Orsay, France; London Regional Cancer Program, Lawson Health Research Institute, London, Ontario, Canada; Department of Biochemistry, Western University, London, Ontario, Canada. Electronic address: mohammedeldika@hotmail.com.

PMID: 32388489
DOI: 10.1016/j.dnarep.2020.102858

No abstract available

Publication types

Letter
Review

MeSH terms

Animals
Apoptosis*
Cell Proliferation
DNA Damage*
DNA Repair*
E2F1 Transcription Factor / metabolism*
Humans
Neoplasms / drug therapy
Neoplasms / metabolism*
Neoplasms / physiopathology
Tumor Protein p73 / metabolism*

Substances

E2F1 Transcription Factor
Tumor Protein p73