Surface-modified magnetic human cells for scaffold-free tissue engineering

Biomater Sci. 2013 Aug 2;1(8):810-813. doi: 10.1039/c3bm60054h. Epub 2013 May 14.

Abstract

We report the magnetically-facilitated scaffold-free assembly of lung tissue mimicking two-layered multicellular clusters. Polymer-stabilized magnetic nanoparticles were deposited on surfaces of viable human cells (A549 and skin fibroblasts), allowing the formation of two-layered porous tissue prototypes.