Inotuzumab ozogamicin resistance associated with a novel CD22 truncating mutation in a case of B-acute lymphoblastic leukaemia

Br J Haematol. 2020 Oct;191(1):123-126. doi: 10.1111/bjh.16949. Epub 2020 Jul 9.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Drug Resistance / genetics*
  • Humans
  • Inotuzumab Ozogamicin / administration & dosage*
  • Male
  • Mutation*
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma* / drug therapy
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma* / genetics
  • Sialic Acid Binding Ig-like Lectin 2 / genetics*

Substances

  • CD22 protein, human
  • Sialic Acid Binding Ig-like Lectin 2
  • Inotuzumab Ozogamicin