The role of the microbiome in host evolution

Philos Trans R Soc Lond B Biol Sci. 2020 Sep 28;375(1808):20190588. doi: 10.1098/rstb.2019.0588. Epub 2020 Aug 10.

Abstract

In the last decade, we have witnessed a major paradigm shift in the life sciences: the recognition that the microbiome, i.e. the set of microorganisms associated with healthy animals (including humans) and plants, plays a crucial role in the sustained health and fitness of its host. Enabled by rapid advances in sequencing technologies and analytical methods, substantial advances have been achieved in both identifying the microbial taxa and understanding the relationship between microbiome composition and host phenotype. These breakthroughs are leading to novel strategies for improved human and animal health, enhanced crop yield and nutritional quality, and the control of various pests and disease agents. This article is part of the theme issue 'The role of the microbiome in host evolution'.

Keywords: beneficial microbes; coevolution; commensals; eco-evolutionary dynamics.

Publication types

  • Introductory Journal Article
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Biological Evolution*
  • Communicable Disease Control*
  • Crops, Agricultural / microbiology*
  • Host Microbial Interactions*
  • Humans
  • Microbiota*
  • Nutritive Value
  • Pest Control*