Immunosurveillance and Regression in the Context of Squamous Pulmonary Premalignancy

Kostyantyn Krysan; Linh M Tran; Steven M Dubinett

doi:10.1158/2159-8290.CD-20-1087

Immunosurveillance and Regression in the Context of Squamous Pulmonary Premalignancy

Cancer Discov. 2020 Oct;10(10):1442-1444. doi: 10.1158/2159-8290.CD-20-1087.

Authors

Kostyantyn Krysan¹, Linh M Tran¹, Steven M Dubinett²

Affiliations

¹ Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, California.
² Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, California. sdubinett@mednet.ucla.edu.

Abstract

In this issue of Cancer Discovery, Pennycuick and colleagues comprehensively evaluate the immune contexture of progressive and regressive lesions in squamous pulmonary premalignancy. The authors dissect the molecular features of these lesions and the potential pathways of immune escape operative in progression to invasive cancer.See related article by Pennycuick et al., p. 1489.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Comment

MeSH terms

Carcinoma, Squamous Cell*
Epithelial Cells
Humans
Lung Neoplasms* / genetics
Monitoring, Immunologic
Precancerous Conditions*

Abstract

Publication types

MeSH terms

Grants and funding