Ciprofloxacin-Resistant Kerstersia gyiorum Isolated From a Chronic Wound in Brazil: A Case Report

Wound Manag Prev. 2020 Oct;66(10):42-45.

Abstract

The presence of Kerstersia gyiorum in lower leg wounds has been reported in case studies from several countries.

Objective: This study evaluated the antimicrobial susceptibility profile of K gyiorum isolated from a chronic wound.

Methods: An 85-year-old woman with chronic venous insufficiency presented to an intermediate care unit in Niteroi City, Rio de Janeiro, Brazil, with an instep chronic wound of 14 cm² with wound duration of 6 months. K gyiorum was identified by matrix-assisted laser desorption ionization-time of flight, confirmed by 16S rRNA partial sequence analysis, and classified as resistant for ciprofloxacin by reagent strips(minimum inhibitory concentration [MIC] = 32 µg/mL) and the broth macrodilution method (MIC = 8 µg/mL). Intermediate resistance for ciprofloxacin was verified by microscan (MIC = 2 µg/mL).

Conclusion: The authors identified the first, to their knowledge, lower leg wound with K gyiorum in Brazil and verified that it was ciprofloxacin resistant.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged, 80 and over
  • Alcaligenaceae / drug effects*
  • Alcaligenaceae / pathogenicity
  • Brazil
  • Ciprofloxacin / therapeutic use*
  • Disease Resistance / drug effects*
  • Female
  • Humans
  • Leg Ulcer / drug therapy*
  • Leg Ulcer / physiopathology
  • Microbial Sensitivity Tests / statistics & numerical data
  • Wound Healing / drug effects*
  • Wound Healing / physiology

Substances

  • Ciprofloxacin

Supplementary concepts

  • Kerstersia gyiorum