V-FAT study - A correlation between novel markers of obesity and coronary artery disease severity assessed by Syntax score in patients presenting with acute coronary syndrome

Anurag Bahekar; Varghese George; Kiran Jacob; Sultan R Salih; Ancy Thannikkal Joseph; Cherian Koshy; Amol Gautam; Geena Benjamin; Krishnan Nair Venugopal

doi:10.1016/j.ihj.2020.07.007

V-FAT study - A correlation between novel markers of obesity and coronary artery disease severity assessed by Syntax score in patients presenting with acute coronary syndrome

Indian Heart J. 2020 Sep-Oct;72(5):448-450. doi: 10.1016/j.ihj.2020.07.007. Epub 2020 Jul 17.

Authors

Anurag Bahekar¹, Varghese George², Kiran Jacob³, Sultan R Salih⁴, Ancy Thannikkal Joseph⁵, Cherian Koshy⁵, Amol Gautam⁶, Geena Benjamin⁷, Krishnan Nair Venugopal⁵

Affiliations

¹ Consultant Interventional Cardiologist, Gondia Care Hospital, Gondia, Maharashtra, India.
² Department of Cardiology, Pushpagiri Institute of Medical Sciences & Research Centre, Thiruvalla, Kerala, India. Electronic address: drvgcardio@outlook.com.
³ Consultant Interventional Cardiologist, Elite Mission Hospital, Thrissur, Kerala, India.
⁴ Consultant Interventional Cardiologist, Sevana Hospital, Palakkad, Kerala, India.
⁵ Department of Cardiology, Pushpagiri Institute of Medical Sciences & Research Centre, Thiruvalla, Kerala, India.
⁶ Department of Radiodiagnosis, Krishna Institute of Medical Sciences, Karad, Maharashtra, India.
⁷ Department of Radiodiagnosis, Pushpagiri Institute of Medical Sciences & Research Centre, Thiruvalla, Kerala, India.

Abstract

Our aim was to evaluate the role of traditional versus newer markers of obesity, in risk assessment of CAD. 50 consecutive ACS patients and 20 controls were enrolled.Visceral and Subcutaneous fat (VFAT and SFAT) analysis was done using multi-slice abdominal MRI. Syntax score was calculated from coronary angiogram. In our study, BMI and Waist/Hip ratios showed poor correlation with Syntax score. VFAT and SFAT showed strong correlation with Syntax score (p-0.01,0.03) and a more significant correlation was noted with their areas at L3-L4 levels (p-0.01,0.05). Statistically significant ROC- area under curve was observed with Indexed SFAT.

Keywords: SFAT; Syntax scoring; VFAT.

MeSH terms

Acute Coronary Syndrome / diagnosis*
Acute Coronary Syndrome / etiology
Coronary Angiography
Coronary Vessels / diagnostic imaging*
Female
Humans
Male
Middle Aged
Obesity / complications*
Obesity / diagnosis
Risk Assessment / methods*
Risk Factors
Severity of Illness Index
Subcutaneous Fat / diagnostic imaging*