Disrupted branched-chain amino acid catabolism impair cardiac insulin signaling and is associated with adverse cardiometabolic outcomes

J Mol Cell Cardiol. 2021 Apr:153:93-94. doi: 10.1016/j.yjmcc.2020.12.011. Epub 2020 Dec 27.

Authors

Dipsikha Biswas¹, Thomas Pulinilkunnil²

Affiliations

¹ Department of Biochemistry and Molecular Biology, Dalhousie University, Dalhousie Medicine New Brunswick, Saint John, New Brunswick, Canada. Electronic address: dp369152@dal.ca.
² Department of Biochemistry and Molecular Biology, Dalhousie University, Dalhousie Medicine New Brunswick, Saint John, New Brunswick, Canada.

PMID: 33378687
DOI: 10.1016/j.yjmcc.2020.12.011

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Amino Acids, Branched-Chain / metabolism*
Animals
Cardiovascular Diseases / etiology
Cardiovascular Diseases / metabolism
Cardiovascular Diseases / pathology*
Heart / physiopathology*
Humans
Insulin / metabolism*
Insulin Resistance*
Metabolic Diseases / etiology
Metabolic Diseases / metabolism
Metabolic Diseases / pathology*
Signal Transduction

Substances

Amino Acids, Branched-Chain
Insulin