Anaesthetic considerations for fertility-sparing surgery and uterine transplantation

Anaesthesia. 2021 Apr:76 Suppl 4:46-55. doi: 10.1111/anae.15389.

Abstract

A number of benign and malignant gynaecological conditions can cause infertility. Advancements in assisted reproductive technologies have facilitated the rapidly evolving subspecialty of fertility preservation. Regardless of clinical indication, women now have the reproductive autonomy to make fully informed decisions regarding their future fertility. In particular, there has been an increasing interest and demand among patients and healthcare professionals for fertility-sparing surgery. Gynaecologists find themselves continually adapting surgical techniques and introducing novel procedures to facilitate this rapidly emerging field and anaesthetists need to manage the consequent physiological demands intra-operatively. Not only is it important to understand the surgical procedures now undertaken, but also the intra-operative management in an ever evolving field. This article reviews the methods of fertility-sparing surgery and also describes important anaesthetic challenges including peri-operative care for women undergoing complex fertility-sparing surgeries such as uterus transplantation.

Keywords: anaesthesia; fertility preservation surgery; fertility-sparing surgery; uterine transplantation.

Publication types

  • Review

MeSH terms

  • Anesthetics / administration & dosage*
  • Endometriosis / pathology
  • Endometriosis / surgery
  • Female
  • Fertility Preservation
  • Humans
  • Leiomyoma / pathology
  • Leiomyoma / surgery
  • Ovarian Neoplasms / pathology
  • Ovarian Neoplasms / surgery
  • Uterine Cervical Neoplasms / pathology
  • Uterine Cervical Neoplasms / surgery
  • Uterus / surgery*
  • Uterus / transplantation

Substances

  • Anesthetics